Low Baseline Pneumococcal Antibody Titers Predict Specific Antibody Deficiency, Increased Upper Respiratory Infections, and Allergy Sensitization

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Selective Antibody Deficiency and its Relation to the IgG2 and IgG3 Subclass Titers in Recurrent Respiratory Infections

Background: Selective antibody deficiency with normal immunoglobulins (SADNI) may be identified as part of distinct primary or secondary immunodeficiency disorders. The clinical manifestations include recurrent, often severe or prolonged, upper or lower respiratory tract infections. Objectives: To evaluate SADNI in patients with recurrent sinopulmonary infections and its relation to IgG subclas...

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Pneumococcal Antibody Titers

Purpose: Immunoglobulin replacement is the mainstay treatment in patients with humoral immunodeficiencies, yet a handful of patients continue to develop sinopulmonary infections while on therapy. The objective of our study was to compare immunoglobulin G (IgG) pneumococcal antibody levels in patients with humoral immune deficiencies who have been on intravenous immunoglobulin (IVIG) replacement...

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Specific antibody deficiency (SAD) with normal immunoglobulin and normal B cells is a primary immunodeficiency characterized by reduced ability to produce antibodies to specific antigens especially polysaccharides. OBJECTIVE To describe the characteristics of patients diagnosed with SAD emphasizing the association between primary immunodeficiency and allergic diseases. PATIENTS AND METHOD D...

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selective antibody deficiency and its relation to the igg2 and igg3 subclass titers in recurrent respiratory infections

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specific antibody deficiency in children suffering recurrent infections

specific antibody deficiency lias been recognized as an immunodeficiency. in order to investigate an antipolysaccliaride antibody defect as a cause of rcccttrent infections, 30 children were studied. patients who had been identified to have a major immunodeficiency or structural abnormality or a disease known to cause infection were excluded. tliirty patints, aged i to 13.8 years (mean age, 5.8...

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ژورنال

عنوان ژورنال: Allergy & Rhinology

سال: 2020

ISSN: 2152-6567,2152-6567

DOI: 10.1177/2152656719900338